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Second, alcoholics, especially homeless alcoholics , have intakes of most vitamins, including vitamin E, well below recommended levels 15 , 21 - Third, vitamin E levels in alcoholics are more dependent on nutritional status and irregular eating habits than liver function impairment Fourth, alcohol consumption as an independent cause of vitamin E deficiency is supported by the fact that discontinuation of alcohol use and resumption of a normal diet or taking vitamin E supplements can result in vitamin E levels returning to the normal range 16 , 17 , Therefore, the way of using this question in the review book to teach vitamin E status in alcoholics to students may at times be abstractive, overly simplified, incomplete, and not fully applicable to clinical realities.
This case study revealed some of the intricacies that are more likely required in the treatment of such a patient — that is, a physician should not assume that a patient like the one in the question is not at risk of vitamin E deficiency. They also developed skills for how to interpret and evaluate information in research articles and use evidence to care for alcoholic patients in the future. This case study demonstrates to us the importance of medical biochemistry materials being taught according to and fitting with medical realities.
We believe that integrating EBM to teaching of biochemistry and molecular biology is a useful approach as it promotes thoughtfulness and healthy skepticism in the student authors, which effectively expands our knowledge base by providing important lessons on the subtleties of clinical medicine during the years of basic science instruction.
Finally, we should emphasize that this is a single case study and that the broad usefulness of our approach remains to be determined.
Further research looking into the usefulness of integrating EBM to teaching and learning various topics of medical biochemistry remain to be investigated in a quantitative way using measurable outcomes. Volume 44 , Issue 1. If you do not receive an email within 10 minutes, your email address may not be registered, and you may need to create a new Wiley Online Library account.
If the address matches an existing account you will receive an email with instructions to retrieve your username. Problem Based Learning.
Joshua M. Samantha L. Search for more papers by this author.
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